Published

Biotechnology

Dynamic Functional Connectivity in Adolescence-Onset Major Depression: Relationships With Severity and Symptom Dimensions.

Published on - Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Authors: Rocco Marchitelli, Marie-Laure Paillère-Martinot, Nadège Bourvis, Christophe Guerin-Langlois, Amélie Kipman, Christian Trichard, Marie Douniol, Coline Stordeur, André Galinowski, Irina Filippi, Gilles Bertschy, Sebastien Weibel, Bernard Granger, Frédéric Limosin, David Cohen, Jean-Luc Martinot, Eric Artiges

See the publication on HAL DOI

The spatial functional chronnectome is an innovative mathematical model designed to capture dynamic features in the organization of brain function derived from resting-state functional magnetic resonance imaging data. Measurements of dynamic functional connectivity have been developed from this model to quantify the brain dynamical self-reconfigurations at different spatial and temporal scales. This study examined whether two spatiotemporal dynamic functional connectivity quantifications were linked to late adolescence-onset major depressive disorder (AO-MDD), and scaled with depression and symptom severity measured with the Montgomery-Åsberg Depression Rating Scale.