Life Sciences

Chronotype, Longitudinal Volumetric Brain Variations Throughout Adolescence, and Depressive Symptom Development

Published on - Journal of the American Academy of Child and Adolescent Psychiatry

Authors: Hélène Vulser, Hervé Lemaître, Stella Guldner, Pauline Bezivin-Frère, Martin Löffler, Anna Sarvasmaa, Jessica Massicotte-Marquez, Eric Artiges, Marie-Laure Paillère Martinot, Irina Filippi, Ruben Miranda, Argyris Stringaris, Betteke Maria van Noort, Jani Penttilä, Yvonne Grimmer, Andreas Becker, Tobias Banaschewski, Arun Bokde, Sylvane Desrivières, Juliane Fröhner, Hugh Garavan, Antoine Grigis, Penny Gowland, Andreas Heinz, Dimitri Papadopoulos Orfanos, Luise Poustka, Michael Smolka, Philip Spechler, Henrik Walter, Robert Whelan, Gunter Schumann, Herta Flor, Jean-Luc Martinot, Frauke Nees, Arun L.W. Bokde

Adolescence is a critical period for circadian rhythm, with a strong shift toward eveningness around age 14. Also, eveningness in adolescence has been found to predict later onset of depressive symptoms. However, no previous study has investigated structural variations associated with chronotype in early adolescence and how this adds to the development of depressive symptoms.