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Life Sciences

Longitudinal Trajectory of the Link Between Ventral Striatum and Depression in Adolescence

Published on - The American Journal of Psychiatry

Authors: Pedro Mario Pan, João Sato, Marie-Laure Paillère Martinot, Jean-Luc Martinot, Eric Artiges, Jani Penttilä, Yvonne Grimmer, Betteke van Noort, Andreas Becker, Tobias Banaschewski, Arun Bokde, Sylvane Desrivières, Herta Flor, Hugh Garavan, Bernd Ittermann, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Juliane Fröhner, Robert Whelan, Gunter Schumann, Margaret Westwater, Christian Grillon, Hugo Cogo-Moreira, Argyris Stringaris, Monique Ernst

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Research in adolescent depression has found aberrant intrinsic functional connectivity (iFC) among the ventral striatum (VS) and several brain regions implicated in reward processing. The present study probes this question by taking advantage of the availability of data from a large youth cohort, the IMAGEN Consortium.