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Life Sciences

Reward Processing in Novelty Seekers: A Transdiagnostic Psychiatric Imaging Biomarker

Published on - Biological Psychiatry

Authors: Shile Qi, Gunter Schumann, Gunter Schumann, Juan Bustillo, Jessica Turner, Rongtao Jiang, Dongmei Zhi, Zening Fu, Andrew Mayer, Victor Vergara, Rogers Silva, Armin Iraji, Jiayu Chen, Eswar Damaraju, Xiaohong Ma, Xiao Yang, Michael Stevens, Daniel Mathalon, Judith Ford, James Voyvodic, Bryon Mueller, Aysenil Belger, Steven Potkin, Adrian Preda, Chuanjun Zhuo, Yong Xu, Congying Chu, Tobias Banaschewski, Gareth Barker, Arun Bokde, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sarah Hohmann, Juliane Fröhner, Michael Smolka, Henrik Walter, Robert Whelan, Vince Calhoun, Jing Sui, Arun L.W. Bokde

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Dysfunctional reward processing is implicated in multiple mental disorders. Novelty seeking (NS) assesses preference for seeking novel experiences, which is linked to sensitivity to reward environmental cues.