Radiogenomics of diffuse intrinsic pontine gliomas (DIPGs): correlation of histological and biological characteristics with multimodal MRI features

Publié le 18 mai 2021 - European Radiology

Auteurs : Raphaël Calmon, Volodia Dangouloff-Ros, Pascale Varlet, Christophe Deroulers, Cathy Philippe, Marie-Anne Debily, David Castel, Kevin Beccaria, Thomas Blauwblomme, David Grevent, Raphael Levy, Charles-Joris Roux, Yvonne Purcell, Ana Saitovitch, Monica Zilbovicius, Christelle Dufour, Stéphanie Puget, Jacques Grill, Nathalie Boddaert

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The diffuse intrinsic pontine gliomas (DIPGs) are now defined by the type of histone H3 mutated at lysine 27. We aimed to correlate the multimodal MRI features of DIPGs, H3K27M mutant, with their histological and molecular characteristics.